Stroke is a major cause of mortality and disability worldwide. Recent scientific and technological advancements have significantly changed the diagnosis and management of acute stroke. The advent of intravenous thrombolysis in the 1990s opened up new opportunities for acute treatment. This has led to a new era of stroke research, focusing on understanding the causes, progression, and treatment of stroke. The global burden of stroke demands constant innovation to prevent recurrent events and minimize long-term disability. This book, compiled from 11 chapters, provides a comprehensive overview of recent developments in stroke care, offering nuanced insights to enhance diagnosis, treatment, and patient care. The Indian Academy of Neurology and Jaypee Brothers Medical Publishers are credited for their support and diligence in bringing this book to life.