Management of Obesity: A Comprehensive Manual for Physicians presents obesity as a multifactorial, chronic, and relapsing disease that contributes to a wide range of cardiometabolic disorders. Designed to bridge the gap between evidence and practice, the book translates current scientific understanding into practical, patient-centered clinical strategies. It offers holistic coverage of obesity—from molecular mechanisms and pathophysiology to prevention and management—with special emphasis on the Indian and South-Asian context. The manual encompasses the full therapeutic spectrum, including lifestyle and behavioral interventions, pharmacotherapy, bariatric and metabolic surgery, and emerging modalities such as digital therapeutics and gut microbiome modulation. Real-world case studies, comparative tables, and concise algorithms make it a valuable clinical resource. Above all, the book highlights that obesity care extends beyond weight reduction, focusing instead on restoring health, functionality, and dignity through empathy and sustained physician–patient partnership.