The 5th edition of the Comprehensive Workbook of Practical and Applied Physiology is a fully updated resource designed in alignment with the latest NMC competency-based curriculum. The book provides a structured, easy-to-follow approach to practical physiology through six well-organized sections covering hematology, experimental and human physiology, calculations, and self-directed learning. It includes “Let’s Think” boxes, flowcharts, and tables to enhance conceptual clarity and clinical application. New additions include chapters on communication skills, AETCOM modules, and CPR (BLS) as per AHA guidelines. With system-based early clinical exposure, practical assessment guidelines, and spot identification exercises, this edition serves as a complete guide to skill development and applied learning in physiology.