This book is a sequel to its 2nd edition that went by the name, Recent Advances and Applied Physics in Imaging (2nd Edition), that was published back in the year 2013. All 28 chapters have been thoroughly revised to give most current knowledge of the topics as this edition goes into press. It not only provides an update on all main imaging modalities, viz. CT, MRI, Ultrasound and Digital Radiography, but also the trending topics such as 'artificial intelligence' and 'deep learning'. Furthermore, it retains the popular topics such as ethical and legal issues in Radiology including PC-PNDT, radiation protection, contrast media, evidence-based radiology with a primer on biostatistics and structured reporting among others. The breadth of knowledge that it offers is vast. This edition will prove to be a useful resource to radiologists and technologists at all levels of training and experience.